(3S)-2-CBZ-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID - Names and Identifiers
Name | (3S)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
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Synonyms | Z-Tic-OH Z-L-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (3S)-2-CBZ-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (S)-(+)-N-CBZ-1,2,3,4-TERTRAHYDRO ISOQUINOLINE-3-CARBOXYLIC ACID (3S)-2-CARBOBENZOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (3S)-2-Carbobenzoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid N-ALPHA-CARBOBENZOXY-L-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (3S)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (3S)-2-phenylmethoxycarbonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid (3S)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (S)-(+)-2-(BENZYLOXYCARBONYL)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID 2,3(1H)-isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(phenylmethyl) ester, (3S)- CBZ-L-7-HYDROXY-(3S)-2-CARBOBENZOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
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CAS | 79261-58-8
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InChI | InChI=1/C18H17NO4/c20-17(21)16-10-14-8-4-5-9-15(14)11-19(16)18(22)23-12-13-6-2-1-3-7-13/h1-9,16H,10-12H2,(H,20,21)/t16-/m0/s1 |
(3S)-2-CBZ-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID - Physico-chemical Properties
Molecular Formula | C18H17NO4
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Molar Mass | 311.33 |
Density | 1.2626 (rough estimate) |
Melting Point | 137-141 °C |
Boling Point | 451.38°C (rough estimate) |
Flash Point | 269.815°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | White to pale yellow |
pKa | 3.86±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 23.5 ° (C=2, MeOH) |
MDL | MFCD00672545 |
(3S)-2-CBZ-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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HS Code | 29334900 |
(3S)-2-CBZ-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID - Introduction
(3S)-2-[(benzyloxy)carbonyl]-1,2,3, acid is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
(3S)-2-[(benzyloxy)carbonyl]-1,2,3,-acid is a white solid, stable at room temperature. It is insoluble in water, but has high solubility in some organic solvents. Its chemical structure contains a tetracyclic isoquinoline skeleton and a carboxylic acid functional group.
Use:
(3S)-2-[(benzyloxy)carbonyl]-1,2,3, As an intermediate in chiral organic synthesis, it has a wide range of applications. It can be used to synthesize other chiral molecules, such as drugs, chemicals and pesticides. Its chiral nature allows it to control the stereoselectivity and catalytic activity of chemical reactions in the synthesis of drugs and chemicals.
Preparation Method:
(3S)-2-[(benzyloxy)carbonyl]-1,2,3, there are many preparation methods for acid. A common method is to synthesize the target product from (S)-benzyl alcohol through a series of chemical conversion reactions, such as ring opening reaction, protection and deprotection, esterification and other steps.
Safety Information:
For specific safety information about (3S)-2-[(benzyloxy)carbonyl]-1,2,3, acid, you need to refer to the safety data sheet of the relevant chemical. Generally speaking, it is a chemical, and care should be taken to follow the relevant laboratory safety procedures. When using or handling the compound, wear appropriate personal protective equipment, such as protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated environment. In addition, avoid inhaling, chewing, or touching the skin of the compound. In case of accident or discomfort, seek medical attention immediately.
Last Update:2024-04-09 21:54:55